Crossing into Uzbekistan from Osh and onwards to Fergana in September 2017
I got to the border at around 8a. Already a significant crowd in front of the Kyrgyz border gate; more significantly, a #very slow# moving crowd. So better arrive earlier than I did. A border guard told me it's basically the same no matter which day.
There are a couple of foreign exchange offices right in front of the border entry gate - I suggest to get some UZS in order to pay for onward transportation, ignoring the fact that the exchange rate there is not the world's best. Also be aware that you may find it difficult to exchange money within Uzbekistan on week ends, so plan accordingly.
It took me more than 90 minutes to pass the entry gate into the Kyrgyz emigration area. Lots of shoving and pushing, lots of body contact; especially elderly ladies were moving quite confidently.
In a sense, it's when queuing that the teachings of the predominant faith in this part of the world tend to break down - teachings which stress separation of sexes, and certainly avoiding of touching between the sexes, as I understand it. Note, however, that once I exited Kyrgyzstan and arrived on the Uzbek side of the border, the Uzbek border guards made sure orderly lines were made, with one line for women, one for men, as one would expect and hope for.
Back to the Kyrgyz side: as you approach the border entry gate, there is a small gate on the left for incoming foot traffic, a small gate on the right for outgoing foot traffic (the long, chaotic, slow moving queue), and a large gate in the middle for vehicular traffic.
If you're a foreign tourist (or handicapped, or carry a baby, or best all of the above) you may approach the large middle gate and hope the border guard will let you in eventually, thereby bypassing the long chaotic queue. I certainly saw a Western couple do exactly that. As I was not in a hurry, and also on some strange personal moral grounds, I stuck to the regular queue together with everybody else.
Once inside the actual border area things went very smoothly. Stamping out on the Kyrgyz side, quick walk to the Uzbek side, getting stamped into Uzbekistan, filling out the Uzbek customs form (Russian only; apparently they keep the expensive English-version form at airports only - ask a border guard for help as I did), then getting the form stamped, onwards through the X-ray machine, then to the manual baggage inspection where - nothing was searched at all! In fact, my bags were not even opened, and no medication was checked or even mentioned, even though my customs form certainly listed a lot of line items. So the Uzbek border experience apparently #can# be quite a pleasant one - perfectly fast, and well organized, in my case.
I took a personal taxi (not shared) with a nice English speaking driver from the border directly to Fergana and paid the driver 250K UZS, around 30 USD at that time. You should be able to get a lower price if you prefer to bargain; I simply told the price I was willing to pay (as I always do) based on an expected travel time of 3 hours and other information I've read on this forum, but it turns out you get into Fergana in less than two hours on excellent roads.